What does Daniel 2:43 mean?
Iron and clay are both useful materials, but they are entirely separate. They cannot be melded together; they can only share boundaries. In the dream which Daniel explains (Daniel 2:31–36), the base of a massive statue is composed of iron mingled with clay. This symbolizes the then-future Roman Empire, which would have an ironlike strength of military power, while also being divided and brittle on the inside.Commentators note various ways in which Rome was divided. Among these were its moral weaknesses. These became worse over time, much as the statue's composition goes from iron, to iron and clay, to individual toes made of clay and iron. Much as there were two legs on the statue, Rome was frequently in conflict between democratic and dictatorial preferences. The jumble of iron and clay, which can never unite, hints at the forced intermingling of cultures and peoples brought about by Rome's military conquest.
Interestingly, Daniel describes the iron and the clay as mixing together in marriage. If two different personalities with different values and attitudes are as resistant to unity as are clay and iron, the relationship is likely to fail. Rome's marriage of iron and clay was doomed from the start and eventually ended.