What does Exodus 4:4 mean?
Moses is concerned that no one will believe his story about speaking to the Lord (Exodus 4:1). God told Moses to throw a staff-like walking stick on the ground, which immediately turned into a snake of some kind (Exodus 4:2–3). This was almost certainly a large cobra or other dangerous species. Moses retreats from it.And yet, the Lord tells Moses to fight natural instinct: to grab the snake by the tail. Despite what some might think, this is actually the safest place to secure a hold on large venomous snakes—assuming the snake isn't coiled and protecting its tail. The concept is still dangerous, so Moses' obedience came with risks. Once the tail is held, the serpent turns back into a staff.
This will serve as a sign that God (Exodus 3:10) truly sends Moses. It will convince the elders of Israel (Exodus 4:30–31). Pharaoh will be harder to persuade; cobras were part of Egyptian religious and political imagery. Court magicians will seem to duplicate the miracle (Exodus 7:11). However, the snake-staff empowered by God will eat those lesser snakes (Exodus 7:10–13).
Despite this, and other signs, Pharaoh and his henchmen will refuse to believe that these are miracles from God (Exodus 7:13). God will give Moses other signs to reinforce his message (Exodus 4:7–9).