What does Genesis 10:12 mean?

This verse concludes the biographical aside about Nimrod in chapter 10's table of nations. Nimrod, a descendant of Noah's son Ham, was a mighty man who established a kingdom of his own in the regions of Shinar and Assyria.

The previous verse revealed that Nimrod established the "great city" of Nineveh in Assyria, along with several other cities. Resen, mentioned in this verse, is the final of Nimrod's cities to be mentioned. The name Resen likely meant "fountainhead," and the city may have been situated on the Tigris river.

In the future, Nimrod's descendants will become some of Israel's greatest enemies. They will also be directly involved in some of the Old Testament's most unfortunate incidents. Among these, as seen in the next chapter, is the incident at the Tower of Babel (Genesis 11:1–9).