What does Isaiah 13:21 mean?
In delivering a message from God, Isaiah has been painting a picture of how radically the city of Babylon will be transformed after God's judgment has fallen on it. The human population will be decimated, leaving no people behind to inhabit it (Isaiah 13:12). The city that was once the pinnacle of human glory and culture in the ancient world will be cut down to nothing.In place of the people, wild animals will make their home in the rubble of the streets. Howling creatures will move into the ruins of the once-opulent homes. Ostriches and goats will dwell there instead of the people who once partied in lavish style.
To some, this recalls pictures of thriving cities during the lockdowns of the COVID–19 pandemic. Famous spots usually swarmed by thousands of tourists and citizens were empty and eerily quiet. In some cases, wild animals were caught by cameras wandering the streets. What's described here is far more severe, like a post-apocalypse story. The area will be entirely ruined and absent from human control. It would not take long for the animal world to reclaim a city that has been emptied of humanity.