What does Isaiah 14:21 mean?
The king of Babylon ruled over many nations with an iron fist and ambitions that reached the heavens. Isaiah has shown that this king imagined he would take his place among the gods after taking control of the world (Isaiah 14:13–14). Instead, his very name will be lost to history, at least as far as the people he ruled over are concerned (Isaiah 14:20).To keep the king's family from becoming a dynasty, the people declare their intention to eliminate his descendants. These potential heirs will pay the price for the crimes against humanity done by their father. They will be killed to eliminate any chance that they emerge, as their father did, and take possession of the world.
Following the death of its powerful king, the time of Babylon will pass away. This king will serve as one more example that the arrogance of human kings is misplaced. Power on earth is given and taken by the Lord (Isaiah 14:22).