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Isaiah 27:12
ESV In that day from the river Euphrates to the Brook of Egypt the Lord will thresh out the grain, and you will be gleaned one by one, O people of Israel.
NIV In that day the Lord will thresh from the flowing Euphrates to the Wadi of Egypt, and you, Israel, will be gathered up one by one.
NASB On that day the Lord will thresh from the flowing stream of the Euphrates River to the brook of Egypt, and you will be gathered up one by one, you sons of Israel.
CSB On that day the Lord will thresh grain from the Euphrates River as far as the Wadi of Egypt, and you Israelites will be gathered one by one.
NLT Yet the time will come when the Lord will gather them together like handpicked grain. One by one he will gather them — from the Euphrates River in the east to the Brook of Egypt in the west.
KJV And it shall come to pass in that day, that the Lord shall beat off from the channel of the river unto the stream of Egypt, and ye shall be gathered one by one, O ye children of Israel.
NKJV And it shall come to pass in that day That the Lord will thresh, From the channel of the River to the Brook of Egypt; And you will be gathered one by one, O you children of Israel.

What does Isaiah 27:12 mean?

Isaiah concludes this larger section (Isaiah 24—27) with a promise from the Lord. In "that day," meaning the end times (Isaiah 2:11; Ezekiel 30:3; Obadiah 1:15; Acts 2:20; 2 Peter 3:10), the Lord will gather up His people of Israel, one by one. The picture Isaiah uses is of a farmer. The farmer takes harvested grain and processes it to remove what is edible. Others will "glean" the field, meaning they will comb the ground to gather in every bit of good grain which has fallen (Leviticus 9:9–10; Ruth 2:2–3).

The Lord will do the same in gathering in the Israelites. The "Brook of Egypt" may refer to the southern border of Israel's rightful territory (Numbers 34:4–5). The space between these two rivers is that of the Promised Land (Genesis 15:18). However, some interpreters think Isaiah's reference is to the Nile River. The following verse refers to people driven into Assyria—represented by the Euphrates—and into Egypt—represented by the Nile (Jeremiah 2:18). This may have been an assurance to the people of Judah that the Lord will not forget those taken into exile in those territories. He will gather up all His lost ones and bring them home.

This theme repeats often in Isaiah's writing (Isaiah 11:12–16 and 35:1–10). The Lord will be faithful to the Israelites all the way to the end, no matter what takes place between now and then.
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