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Isaiah 6:4
ESV And the foundations of the thresholds shook at the voice of him who called, and the house was filled with smoke.
NIV At the sound of their voices the doorposts and thresholds shook and the temple was filled with smoke.
NASB And the foundations of the thresholds trembled at the voice of him who called out, while the temple was filling with smoke.
CSB The foundations of the doorways shook at the sound of their voices, and the temple was filled with smoke.
NLT Their voices shook the Temple to its foundations, and the entire building was filled with smoke.
KJV And the posts of the door moved at the voice of him that cried, and the house was filled with smoke.
NKJV And the posts of the door were shaken by the voice of him who cried out, and the house was filled with smoke.

What does Isaiah 6:4 mean?

The scene Isaiah describes in these verses is filled with dread and awe. The Lord has caused Isaiah to see Him in the temple, seated on a throne, surrounded by multiple angelic, serpent-like, six-winged seraphim. They stand or fly around the room calling out to each other worshipping about the God's holiness and glory (Isaiah 6:1–3). The following verse shows Isaiah is shaken to his core at this scene (Isaiah 6:5).

He now adds that the foundations are shaking from the voices of the seraphim. On top of that, the house is full of smoke. This could be due to smoke of burning incense used in worship or perhaps the "cloud of glory" that sometimes comes when God is near (Exodus 16:10; Isaiah 4:5). In other words, the room is loud, the floor is shaking, the aroma may be intense. And what Isaiah is glimpsing through the thick smoke seems impossible. He knows, though, that it is all terribly real, and that he, as a sinful man, does not belong in such a place (Isaiah 6:5).
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