What does Luke 4:34 mean?
This verse begins with a simple exclamation in Greek: Ea! This is somewhat like English shouts of "Oh!" or "Ahh!" In this context, one could imagine a person shaking their head and waving their hands, as if brushing something away. This is why some translations render the demon saying, "leave us alone!" The spirit's immediate reaction to Jesus (Luke 4:31–33) is a desire that He would go away.Luke's phrasing here uses a plural word: the demon does not say "me" or "I," but specifically says "us." That might mean there is more than one demon involved (Mark 5:9). It might be the demon speaking on behalf of itself and the possessed man. Or this might be a reference to the entire realm of evil spirits—asking what Jesus plans to do with the demons who are in the world.
Beyond mentioning Jesus by name, the demon refers to Him as "the Holy One of God." This echoes the prediction made by Gabriel to Mary before Jesus was born (Luke 1:35). It matches Peter's description of Him (John 6:69). The person to Whom this evil spirit speaks is both fully human (Acts 19:15), as well as God the Son (James 2:19).