What does Luke 8:43 mean?
Jesus is in Galilee, in the middle of a mob. A leader of the synagogue has won His attention on behalf of his dying daughter (Luke 8:40–42), but he is far from the only person in need.None of the Gospel writers identify the unnamed woman's condition. Scholars speculate it was a type of uterine bleeding. In the Mosaic law, such bleeding makes a woman unclean during the time she is bleeding and for a week after. In fact, anyone she touches would be made unclean. They would merely need to wash before evening, but she is barred from worshiping or sacrificing at the temple (Leviticus 15:25–30).
She knows she needs to touch Jesus to be healed (Mark 5:28), but if she does so, she will make Him ceremonially unclean. She doesn't know that He's God, the Son of God, and the Jewish Messiah. She does know He's a respected teacher, healer, and prophet. She doesn't want Him to know she's about to touch Him and make Him unclean, but she's desperate.
Much as with junk medicine of the modern world, many treatments from "healers" of that era were little more than useless spells. That she has spent twelve years unable to properly engage in life and worship makes her willing to try anything. Unfortunately, not only has she lost all her money to false healers, she "suffered much" from their treatments and even grew worse (Mark 5:26).