What does Proverbs 28:26 mean?

The Book of Proverbs defines wisdom as comprehension of God's truth (Proverbs 1:7). Those who reject godliness and His will are defined as "fools." The Bible strongly encourages the use of the mind (Proverbs 14:15; 18:15; Acts 17:11; Romans 12:2; 2 Timothy 3:16–17; Hebrews 5:11–14; 1 John 4:1). Yet it cautions that the human mind must be guided by God's Spirit (Romans 12:1–2). Without submission to God, the human mind is prone to sin and depravity (Jeremiah 17:9; Romans 7:15–19). When Solomon (Proverbs 25:1) warns that it's unwise for a man to "[trust] in his own mind," he means the arrogant, self-centered view which ignores God and puts human preferences above all else (Proverbs 3:5; 9:10; Psalm 49:20; 111:10).

James 3:13–18 contrasts worldly "wisdom" and that from God. First Corinthians 1:19 tells us God will reveal the shallowness of worldly "wisdom," and the ineffectiveness of ungodly reasoning (cf. 1 Corinthians 1:18–31). Christ, the Savior, possesses "all the treasures of wisdom and knowledge" (Colossians 2:3). Instead of relying on our feeble intellect for guidance, we can rely on our all-wise, all-knowing Savior. As the Good Shepherd, He leads His sheep, and it is our responsibility to follow Him (John 10:27). By following the Good Shepherd, we will avoid disaster, which so often comes from sinful choices (Proverbs 8:33; 13:13; 15:24; 18:12).