What does Psalm 108:10 mean?

The original use of these words was in Psalm 60 (Psalm 60:9). In that writing, David prayed for divine help after the nation of Edom launched a surprise attack (Psalm 60:1–5) against a distracted Israelite army (2 Samuel 8:3; 1 Chronicles 18:3). David's earlier writing quickly moved to resolve. He did not intend to abandon faith in the Lord. Psalm 108 combines this with other declarations of trust taken from Psalm 57.

The city mentioned here was probably Sela, better known as Petra. Edom made this their capital, since it was easily defensible in a rocky place. This was a source of pride for the Edomites (Obadiah 1:3), which God intended to thwart (Obadiah 1:4). Here, David's words could either be seen as a question or a rhetorical statement. Perhaps he is asking for God's help in the impending battle. Or he may be asking if the Lord will be with them at all (Psalm 108:11).