What does Revelation 18:22 mean?
These verses continue to poetically describe the fall of "Babylon," used here in reference to the political and economic empire of the "beast" of the end times (Revelation 13:1–10). Revelation mentions many of the common components of a city of culture in explaining the total annihilation of this evil empire. That includes noting that its music, industry, and production will all be dissolved.Music can be used to honor God or to dishonor Him. Psalm 150 calls upon God's people to praise Him with the trumpet, the lute and harp, the tambourine, strings and pipe, and cymbals. Music that honors God lifts the human spirit and assists worshipers to praise God. However, music can dishonor God. Nebuchadnezzar used music to signal his subjects to fall down and worship the image he had erected on the plain of Dura. The king's edict announced: "You are commanded, O peoples, nations, and languages, that when you hear the sound of the horn, pipe, lyre, trigon, harp, bagpipe, and every kind of music, you are to fall down and worship the golden image that King Nebuchadnezzar has set up" (Daniel 3:4–5). Perhaps the beast used music to summon his subjects to worship him. Or he may have used it in connection with sensual practices. However, music is never heard again in fallen Babylon.
Artisans will no longer practice their trades in Babylon. Tools and craftsmen will be completely destroyed when God judges the city. Also, the sound of grinding grain will cease. There will no longer be a need for food because the population will cease to exist.