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Revelation 22:2
ESV through the middle of the street of the city; also, on either side of the river, the tree of life with its twelve kinds of fruit, yielding its fruit each month. The leaves of the tree were for the healing of the nations.
NIV down the middle of the great street of the city. On each side of the river stood the tree of life, bearing twelve crops of fruit, yielding its fruit every month. And the leaves of the tree are for the healing of the nations.
NASB in the middle of its street. On either side of the river was the tree of life, bearing twelve kinds of fruit, yielding its fruit every month; and the leaves of the tree were for the healing of the nations.
CSB down the middle of the city’s main street. The tree of life was on each side of the river, bearing twelve kinds of fruit, producing its fruit every month. The leaves of the tree are for healing the nations,
NLT It flowed down the center of the main street. On each side of the river grew a tree of life, bearing twelve crops of fruit, with a fresh crop each month. The leaves were used for medicine to heal the nations.
KJV In the midst of the street of it, and on either side of the river, was there the tree of life, which bare twelve manner of fruits, and yielded her fruit every month: and the leaves of the tree were for the healing of the nations.
NKJV In the middle of its street, and on either side of the river, was the tree of life, which bore twelve fruits, each tree yielding its fruit every month. The leaves of the tree were for the healing of the nations.

What does Revelation 22:2 mean?

The river in New Jerusalem flows down the city's main street. It may divide and flow around the tree of life. Or perhaps a row of trees flanks the river on each side and produce twelve kinds of fruit, a different fruit each month. There is great meaning attached to the use of a tree: this evokes images of the garden of Eden, where God had originally placed mankind and a tree of life.

The leaves of this tree possess medicinal properties that benefit the nations. If this depiction includes part of the millennial reign of Christ, then earth's regenerate rulers likely shuttle to New Jerusalem to acquire these leaves and carry them back to earth. That would coordinate with the longevity which characterizes life in the millennium. Isaiah 65:20 indicates that a person who dies at age one hundred during the thousand-year reign is young.

Early in human history longer life spans were the norm (Genesis 5), but the advance of sin in the human race and the curse on mankind reduced the life expectancy. With the curse removed by Christ's victory and sin held in check, food will be nutritious, disease will be infrequent, and longevity will return. In eternity, of course, there will no longer be any death, at all (Revelation 20:14).
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