What does Genesis 22:12 mean?
ESV: He said, "Do not lay your hand on the boy or do anything to him, for now I know that you fear God, seeing you have not withheld your son, your only son, from me."
NIV: "Do not lay a hand on the boy," he said. "Do not do anything to him. Now I know that you fear God, because you have not withheld from me your son, your only son."
NASB: He said, 'Do not reach out your hand against the boy, and do not do anything to him; for now I know that you fear God, since you have not withheld your son, your only son, from Me.'
CSB: Then he said, "Do not lay a hand on the boy or do anything to him. For now I know that you fear God, since you have not withheld your only son from me."
NLT: Don’t lay a hand on the boy!' the angel said. 'Do not hurt him in any way, for now I know that you truly fear God. You have not withheld from me even your son, your only son.'
KJV: And he said, Lay not thine hand upon the lad, neither do thou any thing unto him: for now I know that thou fearest God, seeing thou hast not withheld thy son, thine only son from me.
NKJV: And He said, “Do not lay your hand on the lad, or do anything to him; for now I know that you fear God, since you have not withheld your son, your only son, from Me.”
Verse Commentary:
In complete and unhesitating obedience to God, Abraham was preparing to kill Isaac as he lay tied up on an altar. Knife in hand, Abraham is stopped by an urgent voice from heaven calling out his name. Now the angel of the Lord makes it clear: Don't hurt the boy in any way. This was God's plan all along, and Abraham has passed God's test of his faith.

The angel of the Lord, truly the Lord in another form, goes on: Now I know that you fear God since you have not withheld your only son from me. In the Old Testament, especially, to "fear God" means to have such great respect and reverence for the Lord's power and righteousness that you obey Him above all others. God's test satisfied the question of whether Abraham "feared" God once and for all.

Abraham's faith, we should note, is not ignorant or blind. Instead, he is choosing to trust God as a result of prior experiences. Time and again, God has proven that Abraham does not need to understand every detail, he merely needs to obey. God will work to prove His own righteousness in the end. Here, again, this is proven to be the case, though in a far more direct and dramatic form.

The Lord again refers to Isaac as "your son, your only son." We must not miss the parallel to John 3:16: "For God so loved the world, that he gave his only Son, that whoever believes in him should not perish but have eternal life."
Verse Context:
Genesis 22:1–19 takes place over the course of a few days, when Isaac is perhaps a teenager. God commands Abraham to sacrifice his beloved son as a burnt offering. Abraham sets out to obey without hesitation, acting in complete trust that God, somehow, will make all things right. Abraham stops the sacrifice only when the Lord intervenes. For his deep trust and obedience, the Lord renews and emphasizes His blessing on Abraham and his offspring, as well as promising to bless all nations through Abraham's descendants.
Chapter Summary:
In a test of Abraham's faith and obedience, God commands Abraham to do a terrible thing: kill and offer his son Isaac, whom he loves, as a burnt offering. Abraham sets out to obey without hesitation, having finally learned to trust God's goodness over his own misunderstandings. Instead of allowing the boy to be sacrificed, the Lord calls out to Abraham moments before he kills Isaac, laying bound on an altar. Because of Abraham's obedience, God renews and emphasizes His promises of blessing, multiplied offspring, and victory over future enemies.
Chapter Context:
In the previous chapter, the long-promised Isaac was finally born to Sarah and Abraham, while Abraham's other beloved son, Ishmael, was sent away to be cared for by God apart from them. Now God tests Abraham's faith and obedience by commanding him to offer his precious son Isaac as a burnt offering. Abraham sets out to obey without hesitation, stopping only when the Lord cries out to him. For Abraham's obedience, God renews and emphasizes the blessing on him and his offspring. This marks the beginning of the end of Abraham's story, as the book of Genesis transitions to focus on Isaac and his descendants.
Book Summary:
The book of Genesis establishes fundamental truths about God. Among these are His role as the Creator, His holiness, His hatred of sin, His love for mankind, and His willingness to provide for our redemption. We learn not only where mankind has come from, but why the world is in its present form. The book also presents the establishment of Israel, God's chosen people. Many of the principles given in other parts of Scripture depend on the basic ideas presented here in the book of Genesis. Within the framework of the Bible, Genesis explains the bare-bones history of the universe leading up to the captivity of Israel in Egypt, setting the stage for the book of Exodus.
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