What does Hebrews 5:7 mean?
ESV: In the days of his flesh, Jesus offered up prayers and supplications, with loud cries and tears, to him who was able to save him from death, and he was heard because of his reverence.
NIV: During the days of Jesus’ life on earth, he offered up prayers and petitions with fervent cries and tears to the one who could save him from death, and he was heard because of his reverent submission.
NASB: In the days of His humanity, He offered up both prayers and pleas with loud crying and tears to the One able to save Him from death, and He was heard because of His devout behavior.
CSB: During his earthly life, he offered prayers and appeals with loud cries and tears to the one who was able to save him from death, and he was heard because of his reverence.
NLT: While Jesus was here on earth, he offered prayers and pleadings, with a loud cry and tears, to the one who could rescue him from death. And God heard his prayers because of his deep reverence for God.
KJV: Who in the days of his flesh, when he had offered up prayers and supplications with strong crying and tears unto him that was able to save him from death, and was heard in that he feared;
NKJV: who, in the days of His flesh, when He had offered up prayers and supplications, with vehement cries and tears to Him who was able to save Him from death, and was heard because of His godly fear,
Verse Commentary:
Earlier verses explained that a priest offers prayers to God on behalf of the people. Here, Jesus is said to have done the same. In this way, He again fulfills the requirements of a human priest.

The writer of Hebrews has also made mention of Psalm 22, which describes a sinless character crying out to God to be rescued (Psalm 22:24; Hebrews 2:12). Jesus' suffering on the cross brought literal fulfillment to the words of that Psalm. Some believe that the writer of Hebrews may also be referring to Jesus' prayers in the garden of Gethsemane prior to His arrest (Matthew 26:39; Luke 22:42). Jesus' death on the cross was the sacrifice offered, once and for all, for human sin (Hebrews 9:26).

Of course, Jesus was killed by those who arrested Him. The "rescue" He obtained was not from death, but out of death. The resurrection of Jesus was the ultimate sign of His acceptance and approval by God.
Verse Context:
Hebrews 5:1–10 explains how Jesus fits the requirements of a high priest. Earlier verses showed that the Messiah promised by the Old Testament would be entirely human (Hebrews 2:17). That humanity allows Christ to sympathize with our temptations and weaknesses. Here, the writer of Hebrews points out that this also makes Jesus qualified to be our ultimate High Priest. Because of His humanity, His prayers, His sacrifice for sin, and His appointment by God, Jesus' status is far superior to any other figure.
Chapter Summary:
Hebrews chapter 5 completes the previous commentary about Jesus' humanity. His human existence qualifies Him to understand other men and to offer sacrifice to God on our behalf. Jesus also fulfills the roles of both high priest and king, which the author demonstrates by returning to the Old Testament. The figure of Melchizedek is used to illustrate this point: that Christ, unlike any before, was able to be both the kingly Son of David and the High Priest for all people. The deeper meaning of this example, however, may well be lost on the letter's audience, since they are languishing in spiritual immaturity.
Chapter Context:
The book of Hebrews shows how Jesus is the ultimate fulfillment of God's purpose for mankind. For the sake of Jewish Christians, in particular, the author explains that Christ is superior to all other figures, and His covenant is superior to all other relationships. Chapter 5 continues the point made in chapter 4, that Christ's humanity makes Him a uniquely qualified High Priest. This passage bridges that idea into the writer's next warning: spiritual immaturity. This call to avoid apathy will run through all of chapter 6, before the writer returns to Jesus' priesthood in chapter 7.
Book Summary:
The book of Hebrews is meant to challenge, encourage, and empower Christian believers. According to this letter, Jesus Christ is superior to all other prophets and all other claims to truth. Since God has given us Christ, we ought to listen to what He says and not move backwards. The consequences of ignoring God are dire. Hebrews is important for drawing on many portions of the Old Testament in making a case that Christ is the ultimate and perfect expression of God's plan for mankind. This book presents some tough ideas about the Christian faith, a fact the author makes specific note of.
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