What does Isaiah 14:21 mean?
ESV: Prepare slaughter for his sons because of the guilt of their fathers, lest they rise and possess the earth, and fill the face of the world with cities."
NIV: Prepare a place to slaughter his children for the sins of their ancestors; they are not to rise to inherit the land and cover the earth with their cities.
NASB: Prepare a place of slaughter for his sons Because of the wrongdoing of their fathers. They must not arise and take possession of the earth, And fill the surface of the world with cities.'
CSB: Prepare a place of slaughter for his sons, because of the iniquity of their fathers. They will never rise up to possess a land or fill the surface of the earth with cities.
NLT: Kill this man’s children! Let them die because of their father’s sins! They must not rise and conquer the earth, filling the world with their cities.'
KJV: Prepare slaughter for his children for the iniquity of their fathers; that they do not rise, nor possess the land, nor fill the face of the world with cities.
NKJV: Prepare slaughter for his children Because of the iniquity of their fathers, Lest they rise up and possess the land, And fill the face of the world with cities.”
Verse Commentary:
The king of Babylon ruled over many nations with an iron fist and ambitions that reached the heavens. Isaiah has shown that this king imagined he would take his place among the gods after taking control of the world (Isaiah 14:13–14). Instead, his very name will be lost to history, at least as far as the people he ruled over are concerned (Isaiah 14:20).

To keep the king's family from becoming a dynasty, the people declare their intention to eliminate his descendants. These potential heirs will pay the price for the crimes against humanity done by their father. They will be killed to eliminate any chance that they emerge, as their father did, and take possession of the world.

Following the death of its powerful king, the time of Babylon will pass away. This king will serve as one more example that the arrogance of human kings is misplaced. Power on earth is given and taken by the Lord (Isaiah 14:22).
Verse Context:
Chapter 14:3–23 contains a mocking, sarcastic dirge for the fallen king of Babylon. The song imitates the respects otherwise paid to honor a fallen king. Instead, this song describes celebration of both people and trees at his death. The fallen kings in Sheol rise to mock the man for his weakness. The king is sarcastically referred to as the "Day Star"—leading to speculation that this is also a description of Satan's fall from heaven. The fallen one had ambition to become like the Most High among the gods, but instead was cut down to nothing in his death.
Chapter Summary:
After the oracle against Babylon in the previous chapter, Isaiah briefly describes what will follow for Judah. In compassion, the Lord will choose His people once more. He will return them to their homeland. They will sing a mocking taunt-song against the fallen king of Babylon. Isaiah pronounces oracles from the Lord against Assyria and Philistia. The Lord will break the Assyrians in His land. With heavy symbolism, Isaiah seems to prophecy that the Assyrians will defeat the Philistines with a siege four years before it happens. God's people will find refuge in Zion.
Chapter Context:
Chapter 14 follows the oracle about the destruction of Babylon with a brief encouragement to the people of Judah. The Lord will restore them to the land. They will taunt the fallen Babylonian king, using phrases many also associate with the fall of Satan. Isaiah pronounces oracles from the Lord against Assyria and Philistia. He declares that He will break the Assyrians in His land, freeing His people from their oppression. Philistia will fall at the Lord's hand to a famine inflicted on them by a power from the north. Next, Isaiah's prophecy will turn to Moab.
Book Summary:
Isaiah is among the most important prophetic books in the entire Bible. The first segment details God's impending judgment against ancient peoples for sin and idolatry (Isaiah 1—35). The second part of Isaiah briefly explains a failed assault on Jerusalem during the rule of Hezekiah (Isaiah 36—39). The final chapters predict Israel's rescue from Babylonian captivity (Isaiah 40—48), the promised Messiah (Isaiah 49—57), and the final glory of Jerusalem and God's people (Isaiah 58—66).
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