What does Genesis 21:17 mean?
ESV: And God heard the voice of the boy, and the angel of God called to Hagar from heaven and said to her, “What troubles you, Hagar? Fear not, for God has heard the voice of the boy where he is.
NIV: God heard the boy crying, and the angel of God called to Hagar from heaven and said to her, 'What is the matter, Hagar? Do not be afraid; God has heard the boy crying as he lies there.
NASB: God heard the boy crying; and the angel of God called to Hagar from heaven and said to her, 'What is the matter with you, Hagar? Do not fear, for God has heard the voice of the boy where he is.
CSB: God heard the boy crying, and the angel of God called to Hagar from heaven and said to her, "What's wrong, Hagar? Don't be afraid, for God has heard the boy crying from the place where he is.
NLT: But God heard the boy crying, and the angel of God called to Hagar from heaven, 'Hagar, what’s wrong? Do not be afraid! God has heard the boy crying as he lies there.
KJV: And God heard the voice of the lad; and the angel of God called to Hagar out of heaven, and said unto her, What aileth thee, Hagar? fear not; for God hath heard the voice of the lad where he is.
NKJV: And God heard the voice of the lad. Then the angel of God called to Hagar out of heaven, and said to her, “What ails you, Hagar? Fear not, for God has heard the voice of the lad where he is.
Verse Commentary:
The Lord had promised Abraham that Hagar and Ishmael would become a great nation. In other words, they would survive, and Ishmael's offspring would thrive. Based on the scene described in the prior verse, this seems especially unlikely. The pair have been wandering in the wilderness, out of water and with nowhere to go. Hagar has put Ishmael, about 16 years old, under the shade of bush and walked quite a distance away so as not to see him die.

Now, though, God hears and arrives to save. Specifically, an angel of God calls from heaven to tell Hagar that God has heard the voice of the boy. Of course, God could have heard Hagar's voice, as well. It's not clear why the angel emphasizes that God has heard Ishmael's voice. Perhaps it was to comfort Hagar with the understanding that she was not alone in caring about Ishmael; God would care for the boy, as well.

Hagar first met the Lord, also in the wilderness, when she fled from Sarah's wrath after becoming pregnant by Abraham. That time, she called the Lord the "God of seeing." She said she had seen the One who looks after her (Genesis 16:13). Now the Lord makes clear to Hagar that He will look after Ishmael, as well.
Verse Context:
Genesis 21:8–21 describes the painful departure of Hagar and Ishmael from Abraham's life. Now that Isaac is born, Sarah furiously demands that Abraham cast them out. He is greatly displeased, but is told by God that Ishmael will be protected and blessed. So Abraham obeys the Lord and sends them into the wilderness. God steps in and saves the mother and child. He renews his promise to make Ishmael a great nation in his own right. Ishmael grows up in the wilderness, eventually marrying an Egyptian woman.
Chapter Summary:
The Lord did as He had promised. Sarah, now 90 years old, gives birth to Isaac, the long-awaited child. Her joy sours, though, over a fear that Isaac might have to share an inheritance with Ishmael. In obedience to the Lord, who promises to safeguard Ishmael, Abraham sends him and his mother, Hagar, into the wilderness. God rescues them and renews His promise to make Ishmael a great nation in his own right. Meanwhile, Abimelech, king of Gerar, approaches Abraham to make a permanent treaty between them and their descendants. The agreement includes Abraham's possession of a well, at a place which will become known as Beersheba.
Chapter Context:
In the prior chapter, Abraham managed to get Sarah back from Abimelech, following his own deception and God's intervention. Here, Abraham and Sarah finally conceive a natural child. Isaac, the long-awaited child of the promise, is born. In obedience to God, Abraham sends Hagar and Ishmael away. Abimelech approaches Abraham to make a treaty, giving Abraham a permanent home in a place that becomes known as Beersheba. In the following chapter, God will test Abraham's faith and obedience, in one of Scripture's ultimate examples of trust.
Book Summary:
The book of Genesis establishes fundamental truths about God. Among these are His role as the Creator, His holiness, His hatred of sin, His love for mankind, and His willingness to provide for our redemption. We learn not only where mankind has come from, but why the world is in its present form. The book also presents the establishment of Israel, God's chosen people. Many of the principles given in other parts of Scripture depend on the basic ideas presented here in the book of Genesis. Within the framework of the Bible, Genesis explains the bare-bones history of the universe leading up to the captivity of Israel in Egypt, setting the stage for the book of Exodus.
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