What does Isaiah 13:20 mean?
ESV: It will never be inhabited or lived in for all generations; no Arab will pitch his tent there; no shepherds will make their flocks lie down there.
NIV: She will never be inhabited or lived in through all generations; there no nomads will pitch their tents, there no shepherds will rest their flocks.
NASB: It will never be inhabited or lived in from generation to generation; Nor will the Arab pitch his tent there, Nor will shepherds allow their flocks to lie down there.
CSB: It will never be inhabited or lived in from generation to generation; a nomad will not pitch his tent there, and shepherds will not let their flocks rest there.
NLT: Babylon will never be inhabited again. It will remain empty for generation after generation. Nomads will refuse to camp there, and shepherds will not bed down their sheep.
KJV: It shall never be inhabited, neither shall it be dwelt in from generation to generation: neither shall the Arabian pitch tent there; neither shall the shepherds make their fold there.
NKJV: It will never be inhabited, Nor will it be settled from generation to generation; Nor will the Arabian pitch tents there, Nor will the shepherds make their sheepfolds there.
Verse Commentary:
Isaiah has been describing the destruction that will fall on the proud city-state of Babylon when the "day of the Lord" comes for them (Isaiah 13:6; Ezekiel 30:3; Joel 1:15). The city will be attacked, invaded, and the people utterly wiped out. The destruction will be well-earned, but nevertheless cruel, and without mercy (Isaiah 13:19).

This prophecy adds that the city will not be inhabited for all generations. Some scholars suggest that the language here should be read as "many generations." It either case, the city as it was known would no longer exist as a place to live. The dream of Babylon would be dramatically and traumatically ended by the hand of the Lord. The false glory and power of the city would be snuffed out forever.

Isaiah adds that even the wandering nomads, described as "Arabs" in some translations, will not settle in the ruins of Babylon. Shepherds will also not shelter their flocks there for the night. The city will eventually become unfit for human occupation of any kind. Instead, this former showcase for human glory will return to a place for the wild glory of God's animal creation to dwell in (Isaiah 13:21–22).
Verse Context:
Isaiah 13:1–22 contains Isaiah's prophecy from the Lord. This is against the dominant power of Babylon, which would arise after the defeat of the Assyrians. The Lord will assemble and consecrate an international army to attack and obliterate the powerful city-state of Babylon. The people will tremble in fear as the Lord executes His judgment out of His great wrath toward the arrogant and ruthless Babylonians. The population will be slaughtered without mercy and the land left desolate. When it's over, only wild animals will walk the streets of the once-splendid city.
Chapter Summary:
Chapter 13 begins a new section in the book of Isaiah, which focuses on prophecies against other nations besides Israel. It begins by describing the Lord's destruction of the city-state of Babylon. This will come after it has become a dominating power in the world. The Lord will assemble a multi-nation army to attack the city and leave the land completely desolate. All who flee will be hunted and killed. The Medes will slaughter even pregnant women and children without mercy. When it is all over, only wild animals will occupy the once luxurious center of human achievement and sophistication.
Chapter Context:
Isaiah has been discussing the eventual rescue and restoration of Israel (Isaiah 10–12). Chapter 13 introduces an entirely new section in Isaiah's book: prophecies from the Lord against Gentile nations. First is a prediction of the utter destruction of Babylon. That nation had been the dominant power in the world. The Lord will assemble a multi-nation army from near and far to destroy the luxurious and powerful city-state on the Euphrates. This is followed by reassurances and further details of God's vengeance on Israel's other oppressors.
Book Summary:
Isaiah is among the most important prophetic books in the entire Bible. The first segment details God's impending judgment against ancient peoples for sin and idolatry (Isaiah 1—35). The second part of Isaiah briefly explains a failed assault on Jerusalem during the rule of Hezekiah (Isaiah 36—39). The final chapters predict Israel's rescue from Babylonian captivity (Isaiah 40—48), the promised Messiah (Isaiah 49—57), and the final glory of Jerusalem and God's people (Isaiah 58—66).
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