What does Luke 11:51 mean?
ESV: from the blood of Abel to the blood of Zechariah, who perished between the altar and the sanctuary. Yes, I tell you, it will be required of this generation.
NIV: from the blood of Abel to the blood of Zechariah, who was killed between the altar and the sanctuary. Yes, I tell you, this generation will be held responsible for it all.
NASB: from the blood of Abel to the blood of Zechariah, who was killed between the altar and the house of God; yes, I tell you, it shall be charged against this generation.’
CSB: from the blood of Abel to the blood of Zechariah, who perished between the altar and the sanctuary."Yes, I tell you, this generation will be held responsible.
NLT: from the murder of Abel to the murder of Zechariah, who was killed between the altar and the sanctuary. Yes, it will certainly be charged against this generation.
KJV: From the blood of Abel unto the blood of Zacharias, which perished between the altar and the temple: verily I say unto you, It shall be required of this generation.
NKJV: from the blood of Abel to the blood of Zechariah who perished between the altar and the temple. Yes, I say to you, it shall be required of this generation.
Verse Commentary:
Jesus is telling the lawyers of the Pharisees that they are complicit in murdering the same Old Testament prophets they claim to honor. To prove this, God will send a new generation of prophets and apostles—and the lawyers will have a part in their murders. Although we know the Sanhedrin was involved in the murder of Stephen (Acts 7) and tried to murder Paul (Acts 23:12–15), Scripture offers no other specific names besides the apostle James, whom Herod Agrippa I killed (Acts 12:1–3). Even so, we know that before he met Jesus, Paul voted for the execution of many believers (Acts 26:10).

Now, Jesus makes a figure of speech to cover the range of Old Testament prophets who were killed. A prophet is someone who speaks God's words. Abel was a prophet in that he lived out God's will by providing a suitable sacrifice (Genesis 4:1–4; Hebrews 11:4). Out of jealousy of God's approval, Abel's brother Cain murdered him. The first murder victim in human history was a faithful prophet of God (Genesis 4:8).

"Zechariah" probably refers to the son of Jehoiada, the priest who raised and mentored Joash, the king of Judah. While Jehoiada was living, Joash followed God, including restoring the temple and keeping track of the funds so they could be used appropriately. After Jehoiada died, princes of Judah corrupted Joash. He withdrew from worshiping God and turned to Asherim and other idols. Zechariah joined several other prophets to try to return Joash to God. The people attacked Zechariah and demanded Joash have him stoned, which he did (2 Chronicles 24:1–22).

By saying "from the blood of Abel to the blood of Zechariah," Jesus refers to the first and last prophets killed according to the order of the Hebrew canon.

Matthew, however, mentions "Zechariah the son of Barachiah" (Matthew 23:35), though some manuscripts have only "Zechariah." Zechariah the son of Barachiah was a contemporary of Matthew's who was murdered by Zealots under false charges, according to ancient historian Josephus' Jewish War. Although this Zechariah wasn't technically a prophet, he did have the boldness to expose the sins of his accusers.

Luke's account reads, "Yes, I tell you, it will be required of this generation." In Matthew's parallel, which appears to occur much later in Jesus' ministry, Jesus says, "Truly, I say to you, all these things will come upon this generation" (Matthew 23:36).

The two phrases refer to the same thing. It will be required of this generation of lawyers to prove that they revere God's prophets as much as they honor their graves. That trial, or test, will come upon them. Unfortunately, many will fail.
Verse Context:
Luke 11:45–52 comes after descriptions of the cruelty and pride of the Pharisees (Luke 11:39–44). Now, Jesus turns to the lawyers—the experts in the Mosaic law. Greed and wickedness revealed the Pharisees to be like tombs: clean on the outside and filled with death on the inside. The lawyers are said to fill tombs by rejecting God's prophets. In response, the scribes and Pharisees conspire to destroy Jesus (Luke 11:53–54). In the next section, Jesus gives His disciples instructions on how to reject the world and persevere for the sake of the kingdom of God (Luke 12:1—13:9). Jesus will cover this judgment again in Matthew 23.
Chapter Summary:
Jesus teaches the disciples how to pray and explains God's intent to give "good" to those who ask. He then exorcizes a demon and refutes the claim that His power is satanic. Jesus explains that unreasonable skeptics will only see the "sign of Jonah." He then criticizes the superficial legalism of the Pharisees. In response, they plot against Him.
Chapter Context:
In what some scholars refer to as "The Travelogue to Jerusalem" (Luke 9:51—19:27), Jesus prepares His disciples for His crucifixion and resurrection and the establishment of the church. The description begins with Christ teaching the disciples how to spread the news of the kingdom of God and reaffirming how they will be blessed, culminating in the Lord's Prayer (Luke 9:51—11:13). Luke 11 finishes with accounts of leaders who reject Jesus. The remainder of the travelogue gives a pattern of teaching on the kingdom of God, miracles, and explanations of salvation. Then Jesus enters Jerusalem to face the cross.
Book Summary:
Luke was a traveling companion of Paul (Acts 16:10) and a physician (Colossians 4:14). Unlike Matthew, Mark, and John, Luke writes his gospel as an historian, rather than as a first-hand eyewitness. His extensive writings also include the book of Acts (Acts 1:1–3). These are deliberately organized, carefully researched accounts of those events. The gospel of Luke focuses on the earthly ministry of Jesus Christ. Luke's Gentile perspective presents Christ as a Savior for all people, offering both forgiveness and direction to those who follow Him.
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