What does Romans 5:21 mean?
ESV: so that, as sin reigned in death, grace also might reign through righteousness leading to eternal life through Jesus Christ our Lord.
NIV: so that, just as sin reigned in death, so also grace might reign through righteousness to bring eternal life through Jesus Christ our Lord.
NASB: so that, as sin reigned in death, so also grace would reign through righteousness to eternal life through Jesus Christ our Lord.
CSB: so that, just as sin reigned in death, so also grace will reign through righteousness, resulting in eternal life through Jesus Christ our Lord.
NLT: So just as sin ruled over all people and brought them to death, now God’s wonderful grace rules instead, giving us right standing with God and resulting in eternal life through Jesus Christ our Lord.
KJV: That as sin hath reigned unto death, even so might grace reign through righteousness unto eternal life by Jesus Christ our Lord.
NKJV: so that as sin reigned in death, even so grace might reign through righteousness to eternal life through Jesus Christ our Lord.
Verse Commentary:
Previously, Paul has written that one result of Adam's devastating sin was that death came to reign over the lives of humanity (Romans 5:17). Now he writes that death's reign was, in truth, the reign and rule of sin. Sin brings death. Human beings cannot escape our own sin nature no matter how badly we want to. In ourselves, without God's intervention, we will always continue to sin. It rules over us, and it leads to death.

However, Paul has just written that as sin increases, God's grace increases even more. In other words, sin cannot grow past God's capacity to give good to those who deserve His angry judgment instead. Paul concludes that God's grace is the greater ruler. It reigns over sin and death. How? He declares righteous all of us sinners who, by faith, receive his grace-gift of Jesus' death for our sin on the cross.

With death defeated, those who are in Christ will live forever. Grace reigns through righteousness leading to eternal life. But this eternal life is found only through Jesus Christ our Lord. There is no other way to escape the reign of sin and death.

Starting with the next verse, Paul will counter a common and unfortunate response to this idea of abundant grace. Some see God's grace as a license to sin, which is not what God intended, nor what Paul is teaching. The overflowing mercy of God is not a reason to sin, just so that His grace can increase.
Verse Context:
Romans 5:12–21 compares the work of Adam with the work of Christ to show how sin and death came into the world, and how God made a way to escape them. Adam, specially created by God, became the first lawbreaker when he ate from the restricted tree. He brought sin and death to all who came after him. Jesus, hung on a tree—a phrase implying crucifixion—paid for our sin, making it possible for all who believe to reign with Him in eternal life.
Chapter Summary:
Romans 5 begins by describing some of the benefits that come with being declared righteous by God because of our faith in Christ. We have peace with God, and we stand in His grace. We rejoice both in the hope of God's glory and in our temporary suffering. We have hope that will not disappoint, because God has already proved His love for us. Paul then compares the work of Adam in bringing sin and death into the world with the work of Christ in dying for sin in order to offer God's free gift of grace to all who believe.
Chapter Context:
After proving that all men are guilty of sin and incapable of earning salvation, Paul explained how faith—not works—is the means by which God declares us righteous. Romans 5 begins with a powerful, joyful revelation of all that comes with being justified in God's eyes by our faith in Christ. We have peace with God. We stand in God's grace. We have hope for eternal glory and meaning in our current suffering. God has proven His love for us in the death of Christ for our sin while we were still sinners. Adam introduced sin and death to the world, and they continue. Christ, though, by dying for our sin brought God's grace to all who believe. The next chapter begins by refuting a common misconception about salvation by grace through faith.
Book Summary:
The book of Romans is the New Testament's longest, most structured, and most detailed description of Christian theology. Paul lays out the core of the gospel message: salvation by grace alone through faith alone. His intent is to explain the good news of Jesus Christ in accurate and clear terms. As part of this effort, Paul addresses the conflicts between law and grace, between Jews and Gentiles, and between sin and righteousness. As is common in his writing, Paul closes out his letter with a series of practical applications.
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